Thyroid Disease

Graves' disease is an autoimmune disease.

It most commonly affects the thyroid, causing it to grow to twice its size or more (goiter), be overactive, with related hyperthyroid symptoms such as increased heartbeat, muscle weakness, disturbed sleep, and irritability. It can also affect the eyes, causing bulging eyes (exophthalmos).

It affects other systems of the body, including the skin and reproductive organs. It affects up to 2% of the female population, often appears after childbirth, and has a female:male incidence of 5:1 to 10:1. It has a strong hereditary component; when one identical twin has Graves' disease, the other twin will have it 25% of the time.

Smoking and exposure to second-hand smoke is associated with the eye manifestations but not the thyroid manifestations. Diagnosis is usually made on the basis of symptoms, although thyroid hormone tests could be useful, particularly to monitor treatment

GO is often mild and self-limiting, and probably declining in frequency, with only 3–5% of cases posing a threat to eyesight

The thyroid is one of the largest endocrine glands in the body. This gland is found in the neck inferior to (below) the thyroid cartilage (may also be called the Adam's apple in men) and at approximately the same level as the cricoid cartilage. The thyroid controls how quickly the body burns energy, makes proteins, and how sensitive the body should be to other hormones.


  • The thyroid is controlled by the hypothalamus and pituitary. The gland gets its name from the Greek word for "shield", after the shape of the related thyroid cartilage. Hyperthyroidism (overactive thyroid) and hypothyroidism (underactive thyroid) are the most common problems of the thyroid gland
  • What is a thyroid?

    • small, butterfly-shaped gland below the Adam's apple.

  • What does the thyroid do?

    • controlling the body's metabolism by regulating thyroid hormones (T4 and T3)
  • When something goes wrong..


  • What is Graves?

    • Graves' disease, is a condition in which the thyroid gland is hyperactive and the eyes are affected

    • Although Graves' disease could develop at any age and in either sex, it most often affects women 20 to 60 years old




Hypothyroidism Hypothyroidism
Hypothyroidism Hypothyroidism